SMN-Exon7 Mouse anti-Human, Mouse, Clone: 3A8G11, Proteintech

Catalog No.	Quantity
50-173-6352	150 μL

Catalog No. 50-173-6352 Supplier Proteintech Group Inc Supplier No. 602551IG150UL

Description

Mouse Monoclonal Antibody

This antibody, 60255-1-Ig, raised against the C-terminal region (275-294 aa) encoded by the exon 7.

The SMN1 gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein - survival motor neuron protein. The SMN complex plays a catalyst role in the assemble of small nuclear ribonucleoproteins, the building blocks of the spliceosome. Mutations in the SMN1 gene are known to cause spinal muscular atrophy 1/2.

Specifications

• Antigen: SMN-Exon7
• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Classification: Monoclonal
• Clone: 3A8G11
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: SMN1
• Gene Accession No.: P97801, Q16637
• Gene Alias: Component of gems 1, Gemin 1, SMN, SMN1, SMN2, SMNC, SMN-Exon7, SMNT, Survival motor neuron protein, T BCD541
• Gene Symbols: SMN1
• Host Species: Mouse
• Immunogen: SMN-Exon7 Fusion Protein Ag16615
• Purification Method: Protein G
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 20595, 6606
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1