Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Invitrogen™ SMN1 Monoclonal Antibody (2B1)

Mouse Monoclonal Antibody
Supplier: Invitrogen™ MA546549
This item is not returnable.
View return policy
Description
Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. Western blot detects a band of approximately 42 kDa (predicted molecular weight: 35 kDa). For ICC/IF, permeabilize with 0.15% Triton.
The SMN1 gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The telomeric and centromeric copies of this gene are nearly identical and encode the same protein - survival motor neuron protein. The SMN complex plays a catalyst role in the assemble of small nuclear ribonucleoproteins, the building blocks of the spliceosome. Mutations in the SMN1 gene are known to cause spinal muscular atrophy 1/2.
Specifications
| SMN1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with no preservative | |
| P97801, Q16637 | |
| SMN1 | |
| Purified human recombinant His 6 tagged-SMN protein. | |
| 50 μg | |
| Primary | |
| Human, Mouse, Frog | |
| Antibody | |
| IgG1 |
| ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry | |
| 2B1 | |
| Unconjugated | |
| SMN1 | |
| AI849087; BCD541; component of gems 1; Gemin1; Gemin-1; SMA; SMA@; SMA1; SMA2; SMA3; SMA4; Smn; SMN1; SMN2; SMNC; SMNT; survival motor neuron 1; survival motor neuron 1 protein; survival motor neuron protein; survival of motor neuron 1, telomeric; survival of motor neuron protein; T-BCD541; TDRD16A; tudor domain containing 16A | |
| Mouse | |
| Protein A | |
| RUO | |
| 20595, 6606 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction