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Invitrogen™ SMOC1 Polyclonal Antibody
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Catalog No. PIPA531392
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100 μL
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PIPA531392 100 μL
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Catalog No. PIPA531392 Supplier Invitrogen™ Supplier No. PA531392
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: U87-MG. Predicted reactivity: Mouse (96%), Rat (95%), Xenopus laevis (84%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Secreted modular calcium-binding protein 1 (SMOC1) is a gene located on chromosome 14q24.2, encoding a member of the SPARC (Secreted Protein, Acidic, and Rich in Cysteine) family of matricellular proteins. SMOC1 is characterized by its multiple domains that facilitate calcium binding and interaction with various components of the extracellular matrix. This protein plays a crucial role in modulating cell-matrix interactions and signaling pathways involved in cellular adhesion, migration, and differentiation. SMOC1 is expressed in multiple tissues, including the eyes, limbs, and the central nervous system, and is essential for developmental processes such as angiogenesis and tissue formation. Mutations in SMOC1 have been linked to ocular conditions like anterior segment dysgenesis and microphthalmia, reflecting its significance in eye development. Current studies focus on the protein's broader implications in developmental disorders and its potential as a therapeutic target in diseases associated with extracellular matrix dysregulation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SMOC1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene SMOC1
Gene Accession No. Q9H4F8
Gene Alias 2600002F22Rik; AI848508; OAS; secreted modular calcium binding protein 1; secreted modular calcium-binding protein 1; SMOC1; SMOC-1; SPARC related modular calcium binding 1; SPARC-related gene protein; SPARC-related modular calcium binding protein 1; SPARC-related modular calcium-binding protein 1; SPARC-related protein; Srg
Gene Symbols SMOC1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human SMOC1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64093
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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