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Smooth Muscle Myosin Mouse anti-Bovine, Canine, Feline, Rat, Clone: SMMS-1, eBioscience™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

$109.00 - $305.00

Specifications

Antigen Smooth Muscle Myosin
Clone SMMS-1
Target Species Bovine, Canine, Feline, Human, Rat
Conjugate Unconjugated
Isotype IgG1, kappa
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-134-75 Non-distribution product as customer accommodation.
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Invitrogen
14640080
25 μg Each for $109.00
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50-134-76 Non-distribution product as customer accommodation.
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Invitrogen
14640082
100 μg Each for $305.00
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Description

Description

Description: This SMMS-1 monoclonal antibody reacts with both isoforms of the human smooth muscle myosin heavy chain (SM1 and SM2) structural proteins, which are components of the contractile apparatus in smooth muscle cells. Smooth muscle myosin heavy chains are expressed by myoepithelial cells and also serve as the terminal differentiation marker for smooth muscle cells. In normal breast tissue, myoepithelial cells compose the outer layer of the lumen lining. In benign and in situ breast lesions, the intact myoepithelial layer stains with SMMS-1 and the loss of this staining indicates invasive cancer. This SMMS-1 antibody has also been reported to cross-react with bovine, canine, feline, and rat smooth muscle myosin heavy chains. Applications Reported: This SMMS-1 antibody has been reported for use in western blotting, and immunohistochemical staining of formalin-fixed paraffin embedded tissue sections. Applications Tested: This SMMS-1 antibody has been tested by western blot on rat heart and immunohistochemistry on formalin-fixed paraffin embedded tissue (with IHC Antigen Retrieval Solution - Low pH (cat. 00-4955)). This can be used at less than or equal to 5 µg/mL. It is recommended that the antibody be titrated for optimal perfomance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 µm post-manufacturing filtered.

SM-MHC is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmently regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2.
Specifications

Specifications

Smooth Muscle Myosin
Bovine, Canine, Feline, Human, Rat
IgG1, kappa
Monoclonal
Liquid
Antibody
4° C
SMMS-1
Unconjugated
Immunohistochemistry (Paraffin), Western Blot
Primary
Monoclonal
PBS with 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.

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