Invitrogen™ SMPD4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578573

Catalog No. PIPA578573

Description

Predicted Reactivity: Human (100%), Bovine (88%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by SMPD4 is a sphingomyelinase that catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. This gene is activated by DNA damage, cellular stress, and tumor necrosis factor, but it is downregulated by wild-type p53. The encoded protein localizes to the endoplasmic reticulum and Golgi network.

Specifications

• Antigen: SMPD4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SMPD4
• Gene Alias: 4122402O22Rik; Kiaa1418; mKIAA1418; NET13; neutral membrane (neutral sphingomyelinase-3); neutral sphingomyelinase 3; Neutral sphingomyelinase III; neutral sphingomyelinase-3; NSMASE3; nSMase-3; RGD1310674; SKNY; SKNY protein; Smpd4; Sphingomyelin phosphodiesterase 4; sphingomyelin phosphodiesterase 4, neutral membrane; sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 303790, 55627, 77626
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.78 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol, 0.1M glycine and 0.01% thimerosal; pH 7
• Gene Accession No.: Q6ZPR5, Q9NXE4
• Gene Symbols: SMPD4
• Immunogen: Recombinant protein encompassing a sequence within the center region of human SMPD4. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov