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SNAI1 Mouse anti-Human, Clone: OTI10D7, lyophilized, TrueMAB™
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene CF500366

Encompass_Preferred

Catalog No. 50-165-9446


May include imposed supplier surcharges.
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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Zinc finger protein SNAI1 (SNAIL)is a zinc finger transcriptional repressor which down regulates the expression of the ectodermal gene within the mesoderm and functions to form the mesoderm and neural crest. It is reported that SNAI1 acts as an important factor of tumor invasion as evidenced by its role in E-cadherin down-regulation and induction of epithelial-mesenchymal transition (EMT). In human breast cancer, the expression of SNAI1 and/or the homologous SNAI2 (Slug) has been associated with E-cadherin repression, local or distant metastasis, tumor recurrence, or poor prognosis in different tumor series. It is also reported that Snail 1 protein in the stromamay be anew putative prognosis marker for colon tumors.
Specifications

Specifications

SNAI1
Monoclonal
Unconjugated
SNAI1
SLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1
Mouse
Affinity Chromatography
RUO
6615
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Western Blot
OTI10D7
PBS with 8% trehalose and no preservative; pH 7.3
O95863
SNAI1
Full-length protein expressed in 293T cell transfected with human SNAI1 expression vector
100 μg
Primary
Human
Antibody
IgG1
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