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Invitrogen™ SNAIL Monoclonal Antibody (F.31.8)
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Catalog No. PIMA514801 Shop All Thermo Scientific Products
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PIMA514801 100 μL
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Catalog No. PIMA514801 Supplier Invitrogen™ Supplier No. MA514801
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Description

Rabbit Monoclonal Antibody

It is not recommended to aliquot this antibody.

Zinc finger protein SNAI1 (SNAIL)is a zinc finger transcriptional repressor which down regulates the expression of the ectodermal gene within the mesoderm and functions to form the mesoderm and neural crest. It is reported that SNAI1 acts as an important factor of tumor invasion as evidenced by its role in E-cadherin down-regulation and induction of epithelial-mesenchymal transition (EMT). In human breast cancer, the expression of SNAI1 and/or the homologous SNAI2 (Slug) has been associated with E-cadherin repression, local or distant metastasis, tumor recurrence, or poor prognosis in different tumor series. It is also reported that Snail 1 protein in the stromamay be anew putative prognosis marker for colon tumors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SNAIL
Applications Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone F.31.8
Concentration 110 μg/mL
Conjugate Unconjugated
Formulation 0.01M HEPES with 50% glycerol, 0.15M NaCl, 100 μg/mL BSA and <0.02% sodium azide, pH 7.5
Gene Snai1
Gene Accession No. O95863, Q02085
Gene Alias AI194338; dJ710H13.1; Protein sna; protein snail homolog 1; SLUGH2; SNA; Sna protein; Sna1; SNAH; snai; SNAI1; Snail; snail 1; snail 1 homolog; snail 1 zinc finger protein; snail 1, zinc finger protein; snail family transcriptional repressor 1; snail family zinc finger 1; snail homolog 1; Snail1; Zinc finger protein SNAI1
Gene Symbols Snai1
Host Species Rabbit
Immunogen Recombinant human Snail protein.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116490, 20613, 6615
Target Species Human, Mouse, Monkey, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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