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Invitrogen™ SNAIL Polyclonal Antibody
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Catalog No. PIPA585493
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100 μL
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PIPA585493 100 μL
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Catalog No. PIPA585493 Supplier Invitrogen™ Supplier No. PA585493
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Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Predicted reactivity: Mouse (81%), Rat (84%), Bovine (80%). Positive Control: HeLa, Hela (1 ng/mL TGF-beta and 300 ng/mL of EGF for 2 hr), HeLa (starvation for 16 hr, 20 ng/mL TGF-beta and 300 ng/mL EGF treatment for 30 min). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Zinc finger protein SNAI1 (SNAIL)is a zinc finger transcriptional repressor which down regulates the expression of the ectodermal gene within the mesoderm and functions to form the mesoderm and neural crest. It is reported that SNAI1 acts as an important factor of tumor invasion as evidenced by its role in E-cadherin down-regulation and induction of epithelial-mesenchymal transition (EMT). In human breast cancer, the expression of SNAI1 and/or the homologous SNAI2 (Slug) has been associated with E-cadherin repression, local or distant metastasis, tumor recurrence, or poor prognosis in different tumor series. It is also reported that Snail 1 protein in the stromamay be anew putative prognosis marker for colon tumors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SNAIL
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
Classification Polyclonal
Concentration 0.68 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Snai1
Gene Accession No. O95863, Q02085
Gene Alias AI194338; dJ710H13.1; Protein sna; protein snail homolog 1; SLUGH2; SNA; Sna protein; Sna1; SNAH; snai; SNAI1; Snail; snail 1; snail 1 homolog; snail 1 zinc finger protein; snail 1, zinc finger protein; snail family transcriptional repressor 1; snail family zinc finger 1; snail homolog 1; Snail1; Zinc finger protein SNAI1
Gene Symbols Snai1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human SNAI1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116490, 20613, 6615
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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