Invitrogen™ SNX1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA1836

Catalog No. APPH36

Description

PA1-836 detects SNX1 in human and mouse samples. It is recommended for use with recombinant protein. PA1-836 has been successfully used in Western blot and ICC/IF procedures. By Western blot, this antibody detects a ~60 kDa protein representing SNX1in human samples. The PA1-836 immunogen is a synthetic peptide corresponding to residues Q(139) E D Q F D L T V G I T D P E K I(155) of human SNX1. This peptide (Cat. # PEP-286) is available for use in neutralization and control experiments.

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.

Specifications

• Antigen: SNX1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SNX1
• Gene Alias: HsT17379; MGC8664; Snx1; SNX1A; sorting nexin 1; sorting nexin 1A; sorting nexin-1; VPS5
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56440, 6642
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
• Gene Accession No.: Q13596, Q9WV80
• Gene Symbols: SNX1
• Immunogen: Synthetic peptide corresponding to residues Q(139) E D Q F D L T V G I T D P E K I(155) of human SNX1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG