Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA523281

Invitrogen™ SNX2 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA523281
Change view
Click to view available options
Quantity:
100 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA523281 100 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA523281 Supplier Invitrogen™ Supplier No. PA523281
Only null left
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Sequence homology: Platypus/chimpanzee (100%).

Sorting nexin 2 (SNX2) is a gene located on human chromosome 5q23.3 that encodes a protein involved in various cellular processes, primarily associated with endosomal sorting and intracellular trafficking. SNX2, along with SNX1, forms part of the sorting nexin family characterized by the presence of a Phox (PX) domain, which binds phosphoinositides and facilitates the interaction with membrane compartments such as endosomes. Functionally, SNX2 plays roles in the retrograde transport of Shiga toxin from endosomes to the Golgi apparatus, as well as regulation of endosome-endoplasmic reticulum contact sites through interaction with VAP proteins at the ER membrane. Additionally, SNX2 is implicated in autophagy initiation during nutrient starvation by facilitating the tubulation of early endosomes toward ER sites. As a membrane-associated protein, SNX2 is essential for protein trafficking and retrieval of transmembrane proteins, thus contributing to cellular homeostasis and the dynamic remodeling of endosomal zones.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SNX2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA and 0.05% sodium azide
Gene SNX2
Gene Accession No. O60749, Q2TBW7, Q9CWK8
Gene Alias 0610030A03Rik; CTB-36H16.2; hypothetical protein LOC509769; MGC5204; SNX2; sorting nexin 2; sorting nexin-2; Transformation-related gene 9 protein; TRG9; TRG-9
Gene Symbols SNX2
Host Species Rabbit
Immunogen A portion of amino acids 350-400 of human Snx2.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100073099, 474657, 509769, 6643, 67804, 700507
Target Species Human, Mouse, Canine, Monkey, Bovine, Horse, Marsupial, Rhesus Macaque
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.