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  6. SOD2 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 3A6C2, Proteintech 

SOD2 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 3A6C2, Proteintech
SDP

Catalog No. 501736897 Shop All Proteintech Group Inc Products
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50-173-6897 150 μL
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Catalog No. 50-173-6897 Supplier Proteintech Group Inc Supplier No. 664741IG150UL
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Description

Mouse Monoclonal Antibody

Superoxide dismutase (SOD2) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit. The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways. SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor.

Specifications

Antigen SOD2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 3A6C2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene SOD2
Gene Accession No. P04179, P07895, P09671, P28768
Gene Alias IPO B, Mn SOD, MNSOD, SOD2, SODM
Gene Symbols SOD2
Host Species Mouse
Immunogen SOD2 Fusion Protein Ag21388
Purification Method Protein A
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100154319, 20656, 24787, 6648
Target Species Human, Mouse, Pig, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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