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Invitrogen™ SOX1 Polyclonal Antibody
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Catalog No. PIPA523351
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100 μg
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PIPA523351 100 μg
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Catalog No. PIPA523351 Supplier Invitrogen™ Supplier No. PA523351
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Description

Rabbit Polyclonal Antibody

SOX1 Polyclonal Antibody for Western Blot

SOX1, also known as SRY (sex determining region Y)-box 1, is a transcription factor belonging to the SRY-related HMG box family of transcription factors with a HMG box DNA-binding domain. SOX1 works through multiple independent pathways to promote neuronal cell fate determination and differentiation. This nuclear protein acts as a modulator of LINE retroposons promoter activity and is also involved in the development of the central nervous system, mainly neural and lens development. Transcriptional activator SOX1 binds directly to the HES1 promoter and suppresses HES1 transcription, thus attenuating Notch signaling. It also binds to beta-catenin and suppresses beta-catenin-mediated TCF/LEF signaling, thus potentially attenuating the WNT signaling pathway. Expression of SOX1 is seen mostly in embryonic tissues and moderately in brain.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SOX1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA and 0.05% sodium azide
Gene SOX1
Gene Accession No. O00570, P53783, Q2PG84
Gene Alias BB176347; LOC100912302; sex determining region Y-box 1; Sox1; Sox-1; sox1.S; SRY (sex determining region Y)-box 1; SRY box 1; SRY-box 1; SRY-box 1 S homeolog; SRY-box containing gene 1; SRY-box containing protein; SRY-box transcription factor 1; SRY-related HMG-box gene 1; transcription factor SOX-1; transcription factor SOX-1-like; XELAEV_18015596mg; XlSox1; xSox1
Gene Symbols SOX1, sox1.S
Host Species Rabbit
Immunogen A portion of amino acids 100-150 of human SOX1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20664, 6656, 734174, 779569
Target Species Human, Mouse, Monkey, Horse, Frog, Marsupial
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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