Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. 501122858

Invitrogen™ SOX11 Monoclonal Antibody (SOX11-C1), eBioscience™
GREENER_CHOICE

Catalog No. 501122858
Encompass_Preferred
Change view
Click to view available options
Quantity:
100 μg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
50-112-2858 100 μg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. 50-112-2858 Supplier Invitrogen™ Supplier No. 14977382
Add to Cart
Edge
Add to Cart

Description

Mouse Monoclonal Antibody

The monoclonal antibody SOX11-C1 (C1) recognizes human Sox11. The transcription factor Sox11 is a member of the SOX (sex determining region Y-related HMG (High Mobility Group) Box) family of proteins. Under normal conditions Sox11 is expressed in the developing central nervous system during embryogenesis and has sequence homology to Sox4. Sox11 plays a role in neuronal maturation and epithelial-mesenchymal interactions and is required for the survival of neuronal and mesenchymal progenitor cells. Sox11 is expressed in mantle cell lymphoma (MCL) and in subsets of hairy cell leukemias, Burkitt lymphomas, and B cell lymphoblastic leukemias, but is not expressed in other B cell lymphomas or in normal B lymphocytes. Sox11 is also expressed in epithelial ovarian cancer and gliomas. Applications Reported: This SOX11-C1 antibody has been reported for use in flow cytometric analysis, western blotting, immunohistochemical staining of formalin-fixed paraffin embedded tissue sections, and immunocytochemistry. Applications Tested: This SOX11-C1 antibody has been tested by immunohistochemistry of formalin-fixed paraffin embedded tissue using low or high pH antigen retrieval. The antibody can be used at less than or equal to 5 μg/mL. This SOX11-C1 antibody has been tested by immunocytochemistry of fixed and permeabilized cells and can be used at less than or equal to 5 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay...

This intronless gene encodes a member of the SOX family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SOX11
Applications ChIP Assay, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone SOX11-C1
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene SOX11
Gene Accession No. P35716
Gene Alias 1110038H03Rik; 6230403H02Rik; AI836553; end1; MRD27; Sox11; Sox-11; SRY; SRY (sex determining region Y)-box 11; SRY (sex-determining region Y)-box 11; SRY-box 11; SRY-box containing gene 11; SRY-box transcription factor 11; SRY-related HMG-box gene 11; transcription factor SOX-11
Gene Symbols SOX11
Host Species Mouse
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6664
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
Show More Show Less

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.