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Invitrogen™ SOX2 Monoclonal Antibody (20G5), DyLight™ 650
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Catalog No. MA1014D650
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MA1014D650 100 μL
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Catalog No. MA1014D650 Supplier Invitrogen™ Supplier No. MA1014D650
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Description

Mouse Monoclonal Antibody

MA1-014-D650 has been successfully used in ICC/IF applications with human and mouse samples. MA1-014-D650 can be used for immunofluorescence analysis of LIN28 in human iPSCs.

SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of the SOX2 gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Further, SOX2 protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation, optic nerve hypoplasia and syndromic microphthalmia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SOX2
Applications Immunocytochemistry
Classification Monoclonal
Clone 20G5
Concentration 1 mg/mL
Conjugate DyLight 650
Formulation PBS with proprietary stabilizer and 0.02% sodium azide
Gene SOX2
Gene Accession No. P48431, P48432
Gene Alias ANOP3; cb236; Delta EF2a; lcc; MCOPS3; MCOPS3 (Microphthalmia Syndromic type 3); RGD1565646; sex determining region Y-box 2; SOX 2; SOX2; Sox-2; soxp; SRY (sex determining region Y) box 2; SRY (sex determining region Y)-box 2; SRY box 2; SRY related HMG box 2; SRY-box 2; SRY-box 2; SOX2; SRY-box containing gene 2; SRY-box transcription factor 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor SOX-2; wu:fb83g04; wu:fc14d07; ysb; zgc:65860; zgc:77389
Gene Symbols SOX2
Host Species Mouse
Immunogen Full-length human recombinant protein expressed in bacteria.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20674, 6657
Target Species Human, Mouse
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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