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  6. Invitrogen™ SOX2 Recombinant Rat Monoclonal Antibody (Btjce), HRP, Invitrogen™ 

Invitrogen™ SOX2 Recombinant Rat Monoclonal Antibody (Btjce), HRP, Invitrogen™

Catalog No. 502740581
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20 μL
50 μL
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Catalog No. Quantity
50-274-0581 20 μL
74-001-3THRP 50 μL
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Catalog No. 50-274-0581 Supplier Invitrogen™ Supplier No. 740013THRP20UG
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Description

Rat Recombinant Monoclonal Antibody

Recombinant rat monoclonal antibodies are produced using in vitro expression systems. Recombinant antibodies are produced using specific genes that code for the desired antibodies. These genes are cloned into an expression vector and expressed in vitro. The advantages of recombinant antibodies include: better specificity, lot-to-lot consistency, and broader immunoreactivity to diverse targets due to a larger rabbit immune repertoire. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.

SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of the SOX2 gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. The SOX2 gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). Further, SOX2 protein may act as a transcriptional activator after forming a protein complex with other proteins. Mutations in the SOX2 gene have been associated with bilateral anophthalmia, a severe form of structural eye malformation, optic nerve hypoplasia and syndromic microphthalmia.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SOX2
Applications Western Blot
Classification Recombinant Monoclonal
Clone Btjce
Concentration 1.0 mg/mL
Conjugate HRP
Formulation PBS with proprietary stabilizer and proprietary preservative; pH 7.2-7.4
Gene SOX2
Gene Accession No. P48431
Gene Alias ANOP3; cb236; Delta EF2a; lcc; MCOPS3; MCOPS3 (Microphthalmia Syndromic type 3); RGD1565646; sex determining region Y-box 2; SOX 2; SOX2; Sox-2; soxp; SRY (sex determining region Y) box 2; SRY (sex determining region Y)-box 2; SRY box 2; SRY related HMG box 2; SRY-box 2; SRY-box 2; SOX2; SRY-box containing gene 2; SRY-box transcription factor 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor SOX-2; wu:fb83g04; wu:fc14d07; ysb; zgc:65860; zgc:77389
Gene Symbols SOX2
Host Species Rat
Purification Method Affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6657
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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