Invitrogen™ SOX8/SOX9/SOX17/SOX18 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103253

Catalog No. PIPA5103253

Description

Antibody detects endogenous levels of total SOX8/9/17/18.

Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Specifications

• Antigen: SOX8/SOX9/SOX17/SOX18
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SOX18
• Gene Alias: 2010306G03Rik; AI385749; AV220920; CMD1; CMPD1; HLTRS; HLTS; mKIAA4243; Ra; ragged; Ragl; Sox17; Sox-17; SOX18; Sox-18; Sox8; Sox-8; SOX9; Sox-9; SRA1; SRXX2; SRXY10; SRY (sex determining region Y)-box 17; SRY (sex determining region Y)-box 18; SRY (sex determining region Y)-box 8; SRY (sex determining region Y)-box 9; SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal); SRY (sex determining region Y)-box9; SRY (sex-determining region Y)-box 9 protein; SRY box 17; SRY box 18; SRY box 8; SRY box 9; SRY-box 17; SRY-box 18; SRY-box 8; SRY-box 9; SRY-box containing gene 17; SRY-box containing gene 18; SRY-box containing gene 8; SRY-box containing gene 9; Sry-related HMG-box gene 18; SRY-related HMG-box transcription factor SOX17; SRY-related HMG-box, gene 9; transcription factor SOX-17; Transcription factor SOX-18; transcription factor SOX-8; Transcription factor SOX-9; VUR3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 140586, 20671, 20672, 20681, 20682, 302993, 30812, 311723, 312936, 54345, 64321, 6662
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P35713, P43680, P48436, P57073, Q04886, Q04887, Q61473, Q9H6I2
• Gene Symbols: SOX17, SOX18, SOX8, Sox9
• Immunogen: A synthesized peptide derived from human SOX8(Accession P57073), corresponding to amino acid residues K103-E153.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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