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Invitrogen™ SOX8/SOX9/SOX17/SOX18 Polyclonal Antibody
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Catalog No. PIPA5103253
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PIPA5103253 100 μL
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Catalog No. PIPA5103253 Supplier Invitrogen™ Supplier No. PA5103253
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total SOX8/9/17/18.

Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SOX8/SOX9/SOX17/SOX18
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene SOX18
Gene Accession No. P35713, P43680, P48436, P57073, Q04886, Q04887, Q61473, Q9H6I2
Gene Alias 2010306G03Rik; AI385749; AV220920; CMD1; CMPD1; HLTRS; HLTS; mKIAA4243; Ra; ragged; Ragl; Sox17; Sox-17; SOX18; Sox-18; Sox8; Sox-8; SOX9; Sox-9; SRA1; SRXX2; SRXY10; SRY (sex determining region Y)-box 17; SRY (sex determining region Y)-box 18; SRY (sex determining region Y)-box 8; SRY (sex determining region Y)-box 9; SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal); SRY (sex determining region Y)-box9; SRY (sex-determining region Y)-box 9 protein; SRY box 17; SRY box 18; SRY box 8; SRY box 9; SRY-box 17; SRY-box 18; SRY-box 8; SRY-box 9; SRY-box containing gene 17; SRY-box containing gene 18; SRY-box containing gene 8; SRY-box containing gene 9; Sry-related HMG-box gene 18; SRY-related HMG-box transcription factor SOX17; SRY-related HMG-box, gene 9; transcription factor SOX-17; Transcription factor SOX-18; transcription factor SOX-8; Transcription factor SOX-9; VUR3
Gene Symbols SOX17, SOX18, SOX8, Sox9
Host Species Rabbit
Immunogen A synthesized peptide derived from human SOX8(Accession P57073), corresponding to amino acid residues K103-E153.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 140586, 20671, 20672, 20681, 20682, 302993, 30812, 311723, 312936, 54345, 64321, 6662
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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