SP1 Mouse anti-Human, Clone: 4G3H3, Proteintech

Mouse Monoclonal Antibody

Supplier:  Proteintech Group Inc 665081IG150UL

Catalog No. 50-173-6930

Description

SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.

Specifications

• Antigen: SP1
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: P08047
• Gene Symbols: SP1
• Immunogen: SP1 Fusion Protein Ag16720
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 4G3H3
• Conjugate: Unconjugated
• Gene: SP1
• Gene Alias: SP1, Sp1 transcription factor, Transcription factor Sp1, TSFP1
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 6667
• Content And Storage: -20°C
• Form: Liquid