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Invitrogen™ SP1 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA19103

Catalog No. 01-674-383


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Description

Description

This antibody is predicted to react with bovine, canine, porcine and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 16,000.

SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

SP1
Polyclonal
Unconjugated
SP1
1110003E12Rik; AA450830; AI845540; HGNC:11205; SP1; Sp1 transcription factor; Sp1-1; specificity protein 1; trans-acting transcription factor 1; transcription factor Sp1; TSFP1
Goat
Ammonium sulfate precipitation
RUO
6667
-20°C, Avoid Freeze/Thaw Cycles
Liquid
Western Blot
0.5 mg/mL
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
P08047
SP1
Synthetic peptide corresponding to residues CSRIESPNENSNNSQ of human SP1 (aa 68-83).
100 μg
Primary
Human
Antibody
IgG
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