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Tocris Bioscience™ Spadin
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Catalog No. 55941
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55941 1 mg
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Catalog No. 55941 Supplier Tocris Bioscience™ Supplier No. 5594/1
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Description

Potent K2P2.1 (TREK-1) channel blocker

Spadin is a potent TREK-1 channel blocker (IC50 = 71 nM). Enhances dorsal raphe nucleus 5-HT neurotransmission in mice. Induces hippocampal CREB activation and neurogenesis in adult mice. Exhibits antidepressant effects in mouse models of depression. Brain penetrant.

Specifications

Purity 0.95
Description Spadin
Molecular Weight (g/mol) 2012.34
Product Type Spadin
Quantity 1 mg
Sequence Tyr-Ala-Pro-Leu-Pro-Arg-Trp-Ser-Gly-Pro-Ile-Gly-Val-Ser-Trp-Gly-Leu-Arg

For Research Use Only

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