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Invitrogen™ SPAG5 Polyclonal Antibody

Rabbit Polyclonal Antibody

$589.50

Specifications

Antigen SPAG5
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
PIPA5110877
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Invitrogen™
PA5110877
100 μL
Each of 1 for $589.50
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Description

Description

Immunogen sequence: DTVENLTAKL ASTIADNQEQ DLEKTRQYSQ KLGLLTEQLQ SLTLFLQTKL KEKTEQETLL LSTACPPTQE HPLPNDRTFL GSILTAVADE EPESTPVPLL GSDKSAFTRV ASMVSL.

SPAG5 (sperm associated antigen 5), also known as MAP126, hMAP126, DEEPEST or Astrin, is a 1,193 amino acid protein that is expressed at high levels in testis and at lower levels in liver, placenta, pancreas, colon and thymus. Localized specifically to spindle poles during prophase and throughout the spindle during metaphase and anaphase, SPAG5 is essential for proper spindle formation and is thought to be involved in the dynamic and functional regulation of mitotic spindles. Additionally, SPAG5 plays a role in sister chromatid cohesion and subsequent chromatid separation and, via its association with chromatids, is an important regulator of chromosome integrity. SPAG5 has a long stalk and a globular head domain through which if forms a homodimer that is characterized by aster-like structures. Upon DNA damage, SPAG5 may be phosphorylated by ATR or ATM.
Specifications

Specifications

SPAG5
Immunohistochemistry (Paraffin), Western Blot
Unconjugated
Rabbit
RUO
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Q96R06
10615
Recombinant Protein corresonding to Human SPAG5. Recombinant protein control fragment (Product #RP-93178).
Antibody
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Polyclonal
Liquid
IgG
Human
SPAG5
AI874642; Astrin; D11Bhm180e; Deepest; hMAP126; MAP126; Mastrin; microtubule-associated protein; mitotic spindle associated protein p126; mitotic spindle coiled-coil related protein; mitotic spindle-associated protein p126; S17; Spag5; sperm associated antigen 5; sperm-associated antigen 5
SPAG5
Primary
Antigen affinity chromatography
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