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  6. SPATA13 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech 

SPATA13 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501733407 Shop All Proteintech Group Inc Products
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50-173-3407 150 μL
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Catalog No. 50-173-3407 Supplier Proteintech Group Inc Supplier No. 214001AP150UL
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Description

Rabbit Polyclonal Antibody

SPT13 acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.

Specifications

Antigen SPATA13
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration 0.28 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SPATA13
Gene Accession No. Q5DU57, Q96N96
Gene Alias ASEF2, SPATA13, spermatogenesis associated 13
Gene Symbols Spata13
Host Species Rabbit
Immunogen SPATA13 Fusion Protein Ag16101
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 219140, 221178, 305938
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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