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Spectinomycin dihydrochloride pentahydrate, Cell Culture Grade PROMO

Catalog No. J6182014F25
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J6182014F25 25 g
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Catalog No. J6182014F25 Supplier Thermo Scientific Chemicals Supplier No. J6182014PR/DEL

Description

Spectinomycin dihydrochloride pentahydrate, CAS # 22189-32-8, is the hydrochloride salt form of spectinomycin, an aminocyclitol compound showing antibacterial and antimicrobial activities.

General Description

  • Spectinomycin dihydrochloride pentahydrate is derived from Streptomyces spectabilis and presents antibacterial and antimicrobial activities
  • Spectinomycin hydrochloride is a compound that inhibits the 30S ribosomal subunit of bacteria and interrupts protein synthesis and peptide elongation, leading to bacterial cell death

Application

  • Spectinomycin dihydrochloride pentahydrate is a compound that is active against gram-negative bacteria
  • In the laboratory, this compound is used in cell culture applications
  • It prevents contamination and can be used to select for resistant bacteria and plant cells containing the marker gene Spcr
  • It has been used to study respiratory tract infections caused by Pasteurella multocida and Mannheimia haemolytica
  • In genetic approaches, this compound can be used to amplify the plasmid copy number
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 22189-32-8
Molecular Formula C14H36Cl2N2O12
Molecular Weight (g/mol) 495.34 g/mol
MDL Number MFCD00150886
InChI Key DCHJOVNPPSBWHK-UXXUFHFZSA-N
Synonym spectinomycin dihydrochloride
PubChem CID 67108398
ChEBI CHEBI:9217
IUPAC Name dihydrogen (1R,3S,5R,8R,10R,11S,12S,13R,14S)-8,12,14-trihydroxy-5-methyl-11,13-bis(methylamino)-2,4,9-trioxatricyclo[8.4.0.03,8]tetradecan-7-one pentahydrate dichloride
SMILES [H+].[H+].O.O.O.O.O.[Cl-].[Cl-].CN[C@@H]1[C@H](O)[C@H](NC)[C@H]2O[C@]3(O)[C@@H](O[C@H](C)CC3=O)O[C@@H]2[C@H]1O

Specifications

Type Spectinomycin Dihydrochloride Pentahydrate
Physical Form Powder
Color White
Quantity 25 g
Solubility Information Soluble in Water, Soluble in Water, Methanol, Dimethyl sulfoxide, Ethanol and Dimethyl formamide.
Formula Weight 495.35 amu (405.28 amu Anhydrous)
Grade Cell Culture
Chemical Name or Material Spectinomycin dihydrochloride pentahydrate

Safety and Handling

Hazard Category H315-H319-H335
Precautionary Statement P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber 244-554-3
RTECSNumber WG7400000
TSCA No
Recommended Storage Keep Cold
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