Spectinomycin dihydrochloride pentahydrate, Cell Culture Grade

Description

Spectinomycin dihydrochloride pentahydrate, CAS # 22189-32-8, is the hydrochloride salt form of spectinomycin, an aminocyclitol compound showing antibacterial and antimicrobial activities. | CAS: 22189-32-8 | C14H36Cl2N2O12 | 495.34 g/mol

An aminocyclitol antibiotic that binds to the 30S ribosomal subunit of bacteria and interrupts protein synthesis Spectinomycin dihydrochloride pentahydrate is used as an aminocyclitol antibiotic derived from streptomyces spectabilis. It is used in cell culture applications as well as involved in the treatment of gonorrhea. Further, it is used as an anti-bacterial agent to prevent contamination and as a selection agent for resistant bacteria and plant cells.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Spectinomycin dihydrochloride pentahydrate is derived from Streptomyces spectabilis and presents antibacterial and antimicrobial activities
• Spectinomycin hydrochloride is a compound that inhibits the 30S ribosomal subunit of bacteria and interrupts protein synthesis and peptide elongation, leading to bacterial cell death

Application

• Spectinomycin dihydrochloride pentahydrate is a compound that is active against gram-negative bacteria
• In the laboratory, this compound is used in cell culture applications
• It prevents contamination and can be used to select for resistant bacteria and plant cells containing the marker gene Spcr
• It has been used to study respiratory tract infections caused by Pasteurella multocida and Mannheimia haemolytica
• In genetic approaches, this compound can be used to amplify the plasmid copy number

Specifications

Chemical Identifiers

• CAS: 22189-32-8
• Molecular Formula: C14H36Cl2N2O12
• Molecular Weight (g/mol): 495.34
• MDL Number: MFCD00150886
• InChI Key: DCHJOVNPPSBWHK-UXXUFHFZSA-N
• Synonym: Spectinomycin dihydrochloride
• PubChem CID: 67108398
• ChEBI: CHEBI:9217
• IUPAC Name: dihydrogen (1R,3S,5R,8R,10R,11S,12S,13R,14S)-8,12,14-trihydroxy-5-methyl-11,13-bis(methylamino)-2,4,9-trioxatricyclo[8.4.0.0³,⁸]tetradecan-7-one pentahydrate dichloride
• SMILES: [H+].[H+].O.O.O.O.O.[Cl-].[Cl-].CN[C@@H]1[C@H](O)[C@H](NC)[C@H]2O[C@]3(O)[C@@H](O[C@H](C)CC3=O)O[C@@H]2[C@H]1O

• Type: Spectinomycin Dihydrochloride Pentahydrate
• Physical Form: Powder
• Color: White
• Quantity: 5 g
• Solubility Information: Soluble in water;Soluble in water,methanol,dimethyl sulfoxide,ethanol and dimethyl formamide.
• Formula Weight: 495.35 (405.28 Anhydrous)
• Grade: Cell Culture
• Chemical Name or Material: Spectinomycin dihydrochloride pentahydrate

Safety and Handling

Hazard Category	H315-H319-H335
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	244-554-3
RTECSNumber	WG7400000
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only