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Spindly/CCDC99 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501984633
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50-198-4633 100 μL
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Catalog No. 50-198-4633 Supplier Bioss Supplier No. BS2321R
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Description

Rabbit Polyclonal Antibody

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridizations indicate that this lectin is specifically expressed in keratinocytes. It is expressed at all stages of epidermal differentiation (i.e., in basal and suprabasal layers). The protein was found mainly in stratified squamous epithelium. It is moderately repressed by retinoic acid. The antigen localized to basal keratinocytes, although it was also found at lower levels in the suprabasal layers, where it concentrated to areas of cell-to-cell contact. The cellular localization and its striking down-regulation in cultured keratinocytes imply a role in cell-cell and/or cell-matrix interactions necessary for normal growth control.

Specifications

Antigen Spindly/CCDC99
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene SPDL1
Gene Accession No. Q96EA4
Gene Alias 1700018I02Rik; 2600001J17Rik; 2810049B11Rik; AA409762; Arsenite-related gene 1 protein; CCDC99; coiled-coil domain containing 99; Coiled-coil domain-containing protein 99; hSpindly; Protein Spindly; Rhabdomyosarcoma antigen MU-RMS-40.4A; rrhabdomyosarcoma antigen protein MU-RMS-40.4A; Spdl1; Spindle apparatus coiled-coil domain-containing protein 1; spindle apparatus coiled-coil protein 1; spindly homolog
Gene Symbols SPDL1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Protein Spindly.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54908
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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