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Invitrogen™ Spinesin Polyclonal Antibody
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Catalog No. PIPA531485
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PIPA531485 100 μL
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Catalog No. PIPA531485 Supplier Invitrogen™ Supplier No. PA531485
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Rabbit Polyclonal Antibody

Recommended positive controls: MCF-7, mouse brain. Predicted reactivity: Human (99%), Mouse (87%), Rat (87%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Spinesin, also known as Serine protease 22 (PRSS22), is a gene located on chromosome 16p11.2 that encodes a trypsin-like serine protease predominantly expressed in the brain and airway tissues. This protease is part of the large family of serine proteases, characterized by their involvement in a variety of physiological processes, including digestion, immune response, and cellular remodeling. In the nervous system, Spinesin is implicated in synaptic function and plasticity, with potential roles in modulating neural connectivity and communication. It is also involved in processing extracellular matrix components, which can influence cell adhesion and migration, contributing to tissue remodeling and repair processes. Dysregulation of Spinesin expression or activity may impact neural development and has been associated with certain neurological disorders. Research into Spinesin continues to explore its specific functions in the nervous system and its potential therapeutic applications in neurobiology and regenerative medicine.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Spinesin
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.73 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene TMPRSS5
Gene Accession No. Q9ER04, Q9H3S3
Gene Alias adrenal mitochondrial protease; Amp; MGC141886; MGC148044; Spinesin; Tmprss5; Transmembrane protease serine 5; transmembrane protease, serine 5; transmembrane protease, serine 5 (spinesin)
Gene Symbols TMPRSS5
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the Extracellular domain of human Spinesin. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80893, 80975
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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