Spironolactone

Description

CAS: 52-01-7 | C24H32O4S | 416.576 g/mol

Spironolactone used as potassium sparing diuretic. Also used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conn’s syndrome.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in chloroform and methanol. Slightly soluble in water.

Notes
Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.

Specifications

Chemical Identifiers

• CAS: 52-01-7
• Molecular Formula: C24H32O4S
• Molecular Weight (g/mol): 416.576
• MDL Number: MFCD00082250
• InChI Key: LXMSZDCAJNLERA-ZHYRCANASA-N
• PubChem CID: 5833
• ChEBI: CHEBI:9241
• IUPAC Name: S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]-7-yl] ethanethioate
• SMILES: CC(=O)SC1CC2=CC(=O)CCC2(C3C1C4CCC5(C4(CC3)C)CCC(=O)O5)C

• Type: Spironolactone
• Physical Form: Powder
• Melting Point: 207°C to 208°C
• Color: White
• Quantity: 10 g
• Merck Index: 14,8760
• Solubility Information: Soluble in chloroform and methanol. Slightly soluble in water.
• Formula Weight: 416.58
• Chemical Name or Material: Spironolactone

Safety and Handling

Hazard Category	H351-H360F-H373
Hazard Statement	GHS H Statement H360-H302 May damage fertility or the unborn child. Harmful if swallowed.
Precautionary Statement	P201-P202-P260-P281-P308+P313-P501c
EINECSNumber	200-133-6
RTECSNumber	TU4725000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only