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Invitrogen™ SPPL2A Polyclonal Antibody
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Catalog No. PIPA557509
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100 μL
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PIPA557509 100 μL
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Catalog No. PIPA557509 Supplier Invitrogen™ Supplier No. PA557509
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: HASGNGTTKD YCMLYNPYWT ALPSTLENAT SISLMNLTST PLCNLSDIPP VGIKSKAVVV PWGSCHFLE Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 75%.

By searching sequence databases for homologs of Dictyostelium discoideum Impas, which shares homology with presenilin, followed by PCR of lymphocyte and hippocampus cDNA libraries, Grigorenko et al. (2002) cloned SPPL2a. This protein, which may act as an intramembrane protease, contains an N-terminal protease-associated (PA) domain, several transmembrane regions, a hydrophilic loop, conservative sequences around the first and second aspartate residues, and an invariant PAL motif near the C terminus.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SPPL2A
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene SPPL2A
Gene Accession No. Q8TCT8
Gene Alias 2010106G01Rik; C130089K23Rik; IMP3; IMP-3; intramembrane cleaving protease; intramembrane protease 3; MNCb-3763; Presenilin-like protein 2; protein SPPL2a; PSEC0147; PSL2; RGD1563001; signal peptide peptidase like 2A; signal peptide peptidase-like 2A; SPPL2A; SPPL2a protein; SPP-like 2A; SPP-like 2A protein
Gene Symbols SPPL2A
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SPPL2A. Recombinant protein control fragment (Product #RP-95841).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84888
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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