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Invitrogen™ SPRY2 Polyclonal Antibody
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Catalog No. PIPA598172
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100 μg
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PIPA598172 100 μg
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Catalog No. PIPA598172 Supplier Invitrogen™ Supplier No. PA598172
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Rabbit Polyclonal Antibody

SPRY2 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P), ELISA

This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SPRY2
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene SPRY2
Gene Accession No. O43597, Q9QXV8
Gene Alias hSPRY2; IGAN3; MGC23039; protein sprouty homolog 2; sprouty 2; sprouty homolog 2; sprouty homolog 2 (Drosophila); sprouty RTK signaling antagonist 2; sprouty2; SPRY2; spry-2
Gene Symbols SPRY2
Host Species Rabbit
Immunogen Recombinant Human SPRY2 protein (2-97AA).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10253, 24064
Target Species Human, Mouse
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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