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  5. Tocris Bioscience™ SPT Imidazopyridine 1

Tocris Bioscience™ SPT Imidazopyridine 1
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Catalog No. 605550
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60-555-0 50 mg
60-551-0 10 mg
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Catalog No. 60-555-0 Supplier Tocris Bioscience™ Supplier No. 6055/50
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Description

Potent serine palmitoyl transferase inhibitor

SPT Imidazopyridine 1 is a potent serine palmitoyl transferase (SPT) inhibitor (IC50 = 5 nM). Dose-dependently inhibits incorporation of 14C-serine into ceramide. Reduces plasma ceramide levels in vivo. Also increases plasma HDL and reduces vLDL cholesterol levels in rats.

Specifications

Chemical Name or Material 4-[6-(1-Oxoheptyl)imidazo[1,2-a]pyridin-8-yl]benzeneacetic acid
CAS 1933533-18-6
Assay Percent Range >98%
Quantity 50 mg
Molecular Formula C22H24N2O3
Formula Weight Observed MW: 364.44
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