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SPTBN2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501735987 Shop All Proteintech Group Inc Products
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50-173-5987 150 μL
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Catalog No. 50-173-5987 Supplier Proteintech Group Inc Supplier No. 551071AP150UL
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Description

Rabbit Polyclonal Antibody

The antibody is specific to SPTBN2.

Spectrins are principle components of a cell′s membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements.

Specifications

Antigen SPTBN2
Applications Western Blot
Classification Polyclonal
Concentration 0.21 mg/mL
Conjugate Unconjugated
Formulation 0.1 M glycine, 0.1 M sodium bicarbonate with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene SPTBN2
Gene Accession No. O15020
Gene Alias Beta III spectrin, SCA5, Spectrin beta chain, brain 2, Spectrin beta-3, SPTBN2
Gene Symbols SPTBN2
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20743, 6712
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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