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SPTBN2/SCA5 Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Supplier: Bethyl Laboratories, Inc A301117AT
Description
The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Rat
Spectrins are principle components of a cell′s membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009]Specifications
| SPTBN2/SCA5 | |
| Polyclonal | |
| TBS with 0.1% BSA and 0.09% sodium azide | |
| O15020 | |
| SPTBN2 | |
| Between 2340 and 2390 | |
| 20 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| Western Blot | |
| Unconjugated | |
| SPTBN2 | |
| GTRAP41, SCA5 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 6712 | |
| 4° C | |
| Liquid |
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