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Selleck Chemical LLC Cilofexor

Supplier: Selleck Chemical LLC S65475MG

Cilofexor(GS-9674) is a potent selective oral agonist of farnesoid X receptor (FXR) with an EC50 of 43 nM It has demonstrated anti-inflammatory antifibrotic effects and reduced portal pressure in preclinical liver fibrosis models showing potential therapeutic benefit for primary sclerosing cholangitis (PSC) and nonalcoholic steatohepatitis (NASH) research
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