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Tocris Bioscience™ SR 7826
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Catalog No. 562650
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Catalog No. 562650 Supplier Tocris Bioscience™ Supplier No. 5626/50
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Description

Potent and selective LIMK inhibitor; antitumor

SR 7826 is a potent and selective LIMK inhibitor (IC50 values are 43, 5536 and 6565 nM for LIMK1, ROCKI and ROCKII, respectively). Inhibits cofilin phosphorylation in A7r5 cells and suppresses migration and invasion of PC-3 cells in vitro. Orally bioavailable.

Specifications

Chemical Name or Material N-(2-Hydroxyethyl)-N′-[4,5-methyl-7H-pyrrolo[2,3-d]pyrimidine-4-yl)phenyl]-N-phenylurea
CAS 1219728-20-7
Quantity 50 mg
Target LIMK Inhibitors
Molecular Formula C22H21N5O2
Formula Weight 387.43
Purity >98%
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