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  5. Tocris Bioscience™ SR 9238

Tocris Bioscience™ SR 9238

Catalog No. 585410
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Quantity:
10 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and selective LXR inverse agonist

SR 9238 is a potent and selective LXR inverse agonist (IC50 values are 43 and 214 nM for LXRβ and LXRα, respectively). Selectively inhibits liver LXR over peripheral LXR. Exhibits selectivity for LXR over a panel of 20 other nuclear receptors, including FXR. Reduces hepatic steatosis in obese mice.

Specifications

Chemical Name or Material Ethyl 5-[[[[3′-(Methylsulfonyl)[1,1′-biphenyl]-4-yl]methyl][(2,4,6-trimethylphenyl)sulfonyl]amino]methyl]-2-furancarboxylate
CAS 1416153-62-2
Quantity 10 mg
Target LXR-like Receptor Antagonists
Molecular Formula C31H33NO7S2
Formula Weight 595.73
Purity >98%
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