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Invitrogen™ SR-BI Polyclonal Antibody
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Catalog No. APSA6786
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APSA6786 100 μL
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Catalog No. APSA6786 Supplier Invitrogen™ Supplier No. PA316786
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Rabbit Polyclonal Antibody

Suggested positive control: mouse liver lysate or protein.

High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidgenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, it seems that SR-BI plays a key role in determining the levels of plasma lipoprotein cholesterol and the accumulation of cholesterol stores in the adrenal gland.
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Specifications

Antigen SR-BI
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene SCARB1
Gene Accession No. O18824, P97943, Q60417, Q61009, Q8WTV0
Gene Alias AI120173; CD36; CD36 and LIMPII analogous 1; CD36 antigen (collagen type I receptor thrombospondin receptor)-like 1 (scavanger receptor class B type 1); CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1; CD36 antigen (collagen type I receptor, thrombospondin receptor-like 1); CD36 antigen-like 1; Cd36l1; CD36-related class B scavenger receptor haSR-BI; CLA1; Cla-1; Collagen type I receptor, thrombospondin receptor-like 1; D5Ertd460e; haSR-bI; HDL QTL 1; Hdlq1; HDLQTL6; high density lipoprotein receptor; Hlb398; mSR-BI; Scarb1; scavanger receptor class B type 1; scavenger receptor b1; scavenger receptor class B member 1; scavenger receptor class B type I; scavenger receptor class B type II; scavenger receptor class B type III; scavenger receptor class B, member 1; scavenger receptor class B1; SRB1; SR-B1; SRBI; SR-BI; SR-BII
Gene Symbols SCARB1
Host Species Rabbit
Immunogen A C-terminal peptide containing residues from mouse SR-BI (within residues 450-509).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100736552, 20778, 25073, 282346, 949
Target Species Human, Mouse, Rat, Monkey, Bovine, Hamster, Mustelid, Flatworm
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer and Reproductive Harm - www.P65Warnings.ca.gov
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