Invitrogen™ SRC1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA1840

Catalog No. PA1840

Description

PA1-840 detects steroid receptor coactivator-1 (SRC-1) from human, mouse, and japaneese quail tissues and cells. PA1-840 has been successfully used in Western blot, immunocytochemistry and immunohistochemistry procedures. By Western blot, this antibody detects an ~165 kDa protein representing SRC-1 and a smaller, unknown protein at ~40 kDa from HeLa cell lysate. Immunocytochemical staining of SRC-1 in HeLa cells with PA1-840 results in nuclear staining. The PA1-840 immunogen is a synthetic peptide corresponding to residues S(8) S D P A N P D S H K R K G S P C(24) of human SRC-1. This immunizing peptide (Cat. # PEP-044) is available for use in neutralization and control experiments.

Clone 1135 recognizes SRC-1, steroid-receptor coactivator-1. SRC-1 is a member of a gene family that functions in the full transcriptional activation of the steroid hormone receptor superfamily and contains intrinsic histone acetyltransferase activity. SRC-1 has a molecular weight of 160 kDa and has a basic helix-loop-helix (bHLH)-PAS domain.

Specifications

• Antigen: SRC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: NCOA1
• Gene Alias: ASV; bHLHe42; bHLHe74; class E basic helix-loop-helix protein 74; c-SRC; F-SRC-1; Hin-2 protein; KAT13A; mNRC-1; NCOA1; NCoA-1; Nuclear receptor coactivator 1; nuclear receptor coactivator protein 1; p60-Src; PAX3/NCOA1 fusion protein; Protein Hin-2; Renal carcinoma antigen NY-REN-52; RIP160; Src1; SRC-1; SRC-1 (-Q); SRC-a/NCoA-1; Steroid receptor coactivator 1; steroid receptor coactivator-1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17977, 8648
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Frozen), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
• Gene Accession No.: P70365, Q15788
• Gene Symbols: NCOA1
• Immunogen: Synthetic peptide corresponding to residues S(8) S D P A N P D S H K R K G S P C(24) of human SRC-1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Avian
• Product Type: Antibody
• Isotype: IgG