Invitrogen™ SRPK3 Polyclonal Antibody

Catalog No.	Quantity
PA550795	100 μL

Catalog No. PA550795 Supplier Invitrogen™ Supplier No. PA550795

Description

Rabbit Polyclonal Antibody

The antibody detects endogenous levels of total STK23 protein.

STK23 (MSSK1), also known as SRPK3, is a muscle-specific member of the SRPKs. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

Specifications

• Antigen: SRPK3
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene: SRPK3
• Gene Accession No.: Q9UPE1
• Gene Alias: MSSK1; MSSK-1; muscle-specific serine kinase 1; muscle-specific serine kinase 1; MSSK1; serine arginine rich protein-specific kinase 3; serine/arginine-rich protein specific kinase 3; serine/arginine-rich protein-specific kinase 3; serine/threonine kinase 23; serine/threonine kinase 23, muscle-specific serine kinase 1 70; serine/threonine-protein kinase 23; serine/threonine-protein kinase SRPK3; SFRS protein kinase 3; Srpk3; SR-protein-specific kinase 3; SRSF protein kinase 3; STK23
• Gene Symbols: SRPK3
• Host Species: Rabbit
• Immunogen: Fusion protein corresponding to residues near the C terminal of human SRSF protein kinase 3.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 26576
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG