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Invitrogen™ SRSF11 Polyclonal Antibody
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Catalog No. PIPA537056
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PIPA537056 100 μL
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Catalog No. PIPA537056 Supplier Invitrogen™ Supplier No. PA537056
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Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 54 kDa. Purity is >95% by SDS-PAGE.

Pre-mRNA splicing enhancer elements are short RNA sequences capable of activating weak splice sites in nearby introns that are required for accurate splice site recognition and the control of alternative splicing. Splicing enhancer elements contain specific binding sites for serine/arginine (SR)-rich splicing factors, which include SC35, 9G8, SRp20 and SF2/ASF. The family of SR factors all contain one or more RNA recognition motifs (RRM) and a SR-rich domain. The SR factor family is not only essential for constitutive splicing, but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. SFRS11 (splicing factor, arginine/serine-rich 11), also known as arginine-rich 54 kDa nuclear protein (p54) or NET2, is a 484 amino acid nuclear protein that colocalizes with spliceosome components and belongs to the splicing factor SR family. SFRS11 may function in pre-mRNA splicing and contains one RRM (RNA recognition motif) domain.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SRSF11
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene SRSF11
Gene Accession No. Q05519
Gene Alias 0610009J05Rik; 2610019N13Rik; Arginine-rich 54 kDa nuclear protein; BF642805; dJ677H15.2; NET2; p54; serine and arginine rich splicing factor 11; serine/arginine-rich splicing factor 11; SFR11; Sfrs11; splicing factor p54; splicing factor, arginine/serine-rich 11; SR splicing factor 11; Srsf11
Gene Symbols SRSF11
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 260-305 of human SRSF11.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 502603, 69207, 9295
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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