Invitrogen™ SRSF2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA512402

Catalog No. PIPA512402

Description

This antibody is predicted to react with bovine, chicken, mouse, porcine and rat based on sequence homology.

The protein encoded by SC35 is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for SC35. In addition, a pseudogene of SC35 has been found on chromosome 11.

Specifications

• Antigen: SRSF2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SRSF2
• Gene Alias: D11Wsu175e; MRF-1; myelin regulatory factor 1; Pr264; Protein PR264; Putative myelin regulatory factor 1; SC35; SC-35; serine and arginine rich splicing factor 2; serine/arginine-rich splicing factor 2; Sfrs10; Sfrs2; SFRS2A; splicing component, 35 kDa; Splicing factor SC35; splicing factor, arginine/serine-rich 2; splicing factor, arginine/serine-rich 2 (SC-35); SR splicing factor 2; SRp30b; Srsf2
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
• Regulatory Status: RUO
• Gene ID (Entrez): 6427
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 2 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q01130
• Gene Symbols: SRSF2
• Immunogen: KLH conjugated synthetic peptide between 9-39 amino acids from the N-terminal region of human SFRS2.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG