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SS18 Mouse anti-Human, Clone: OTI4F11, liquid, TrueMAB™
SDP

Catalog No. 501683085
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50-168-3085 100 μL
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Catalog No. 50-168-3085 Supplier OriGene Supplier No. TA809897
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Mouse Monoclonal Antibody

The transcriptional coactivator SYT (synovial translocation protein) contains a conserved amino terminal SNH domain and a carboxy terminal QPGY domain, which is a functioning transcriptional activating sequence. Synovial sarcoma translocation (SSX) proteins, including SSX1-5, are transcriptional repressors that contain a repressor domain in their carboxy termini. SSX proteins are localized to the nucleus and expressed in testis and several types of cancers and, therefore, they are classified as C/T (cancer/testis) antigens. The t(x;18) translocation results in the fusion of the amino terminus of SYT to the carboxy terminus of either SSX1 or SSX2; both fusions result in the production of transcriptional activators.

Specifications

Antigen SS18
Applications Western Blot
Classification Monoclonal
Clone OTI4F11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene SS18
Gene Accession No. Q15532
Gene Alias SSXT, SYT
Gene Symbols SS18
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 227-255 of human SS18 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6760
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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