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Invitrogen™ SSEA1 Monoclonal Antibody (MC-480)
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Catalog No. 411200
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41-120-0 100 μg
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Catalog No. 41-120-0 Supplier Invitrogen™ Supplier No. 411200
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Description

Mouse Monoclonal Antibody

SSEA1 Monoclonal Antibody for Flow, ICC/IF, Western Blot

CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SSEA1
Applications Flow Cytometry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone MC-480
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.4
Gene FUT4
Gene Accession No. P22083, Q11127
Gene Alias FUTIV; Lewis X; SSEA-1
Gene Symbols FUT4
Host Species Mouse
Immunogen X-irradiated F9 teratocarcinoma stem cells.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14345, 2526
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgM
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