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Invitrogen™ SSEA1 Monoclonal Antibody (MC-480), DyLight™ 488
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Catalog No. MA1022D488
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MA1022D488 100 μL
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Catalog No. MA1022D488 Supplier Invitrogen™ Supplier No. MA1022D488
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Description

Mouse Monoclonal Antibody

MA1-022-D488 has been successfully used in ICC/IF and flow cytometry applications on mouse and human samples.

CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SSEA1
Applications Flow Cytometry, Immunocytochemistry
Classification Monoclonal
Clone MC-480
Concentration 1 mg/mL
Conjugate DyLight 488
Formulation PBS with proprietary stabilizer and 0.02% sodium azide
Gene FUT4
Gene Accession No. P22083, Q11127
Gene Alias FUTIV; Lewis X; SSEA-1
Gene Symbols FUT4
Host Species Mouse
Immunogen BALB/c mouse immunized with F9 teratocarcinoma stem cells (X-irradiated).
Purification Method Affinity chromatography - MBP
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14345, 2526
Target Species Human, Mouse
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgM
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