Invitrogen™ SSEA1 Monoclonal Antibody (VIMC6), PE

Catalog No.	Quantity
MHCD1504	500 μL

Catalog No. MHCD1504 Supplier Invitrogen™ Supplier No. MHCD1504

Description

Mouse Monoclonal Antibody

R-phycoerythrin (PE) is a stable and highly soluble phycobiliprotein which provides maximal absorbance and fluorescence without susceptibility to internal or external fluorescence quenching, thus providing an exceptional quantum yields and molar extinction coefficients.

CD15 (Lewis X, Le(x); stage specific embryonic antigen-1, SSEA-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumour cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin's disease.

Specifications

• Antigen: SSEA1
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: VIMC6
• Conjugate: PE
• Formulation: PBS with BSA and 0.1% sodium azide
• Gene: FUT4
• Gene Accession No.: P22083
• Gene Alias: FUTIV; Lewis X; SSEA-1
• Gene Symbols: FUT4
• Host Species: Mouse
• Immunogen: Human CD15.
• Purification Method: Purified
• Quantity: 500 μL
• Regulatory Status: ASR
• Primary or Secondary: Primary
• Gene ID (Entrez): 2526
• Target Species: Human
• Content And Storage: 4°C, store in dark
• Product Type: Antibody
• Form: Liquid
• Isotype: IgM