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Description
MA1-021-D550 has been successfully used in ICC/IF and flow cytometry applications on human samples.
SSEA-4 (Stage-specific embryonic antigen 4) is a cell surface antigen, expressed along with SSEA-3, TRA-1-60 and TRA-1-81 in embryonic stem cells, embryonal carcinoma cells and induced pluripotent stem cells (iPS). In human cells, these surface markers are down-regulated during the differentiation process, while SSEA-1 is absent in undifferentiated human stem cells and upregulated on the cell surface after retinoic acid mediated differentiation. Conversely, in mouse stem cells, SSEA-1 expression decreases with differentiation while SSEA-3 and SSEA-4 expression increase.
Specifications
Specifications
| Antigen | SSEA4 |
| Applications | Flow Cytometry, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | MC-813-70 |
| Concentration | 1 mg/mL |
| Conjugate | DyLight 550 |
| Formulation | PBS with proprietary stabilizer and 0.02% sodium azide |
| Gene Alias | SSEA-4; stage-specific embryonic antigen 4 |
| Host Species | Mouse |
| Immunogen | human embryonal carcinoma cell line 2102Ep. |
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Safety and Handling
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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