Invitrogen™ ST5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA595166

Catalog No. PIPA595166

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Rat Testis Tissue, A431 whole cell, HELA whole cell, COLO320 whole cell, NIH/3T3 whole cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.

Specifications

• Antigen: ST5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DENND2B
• Gene Alias: 2010004M01Rik; 2610305K15Rik; DENN domain-containing protein 2B; DENN/MADD domain containing 2B; DENND2B; HeLa tumor suppression 1; HTS1; p126; p70; St5; suppression of tumorigenicity 5; suppression of tumorigenicity 5 protein
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 308944, 6764, 76954
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
• Gene Accession No.: P78524, Q924W7
• Gene Symbols: DENND2B
• Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human ST5 (571-586aa KRHSHDDMLLLAQLSL).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov