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Invitrogen™ ST5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA595166

Catalog No. PIPA595166


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Description

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Rat Testis Tissue, A431 whole cell, HELA whole cell, COLO320 whole cell, NIH/3T3 whole cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

ST5
Polyclonal
Unconjugated
DENND2B
2010004M01Rik; 2610305K15Rik; DENN domain-containing protein 2B; DENN/MADD domain containing 2B; DENND2B; HeLa tumor suppression 1; HTS1; p126; p70; St5; suppression of tumorigenicity 5; suppression of tumorigenicity 5 protein
Rabbit
Affinity chromatography
RUO
308944, 6764, 76954
-20°C
Lyophilized
Western Blot
500 μg/mL
PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
P78524, Q924W7
DENND2B
A synthetic peptide corresponding to a sequence in the middle region of human ST5 (571-586aa KRHSHDDMLLLAQLSL).
100 μg
Primary
Human, Mouse, Rat
Antibody
IgG
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