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Invitrogen™ ST5 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA595166
Description
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Rat Testis Tissue, A431 whole cell, HELA whole cell, COLO320 whole cell, NIH/3T3 whole cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.
Specifications
ST5 | |
Polyclonal | |
Unconjugated | |
DENND2B | |
2010004M01Rik; 2610305K15Rik; DENN domain-containing protein 2B; DENN/MADD domain containing 2B; DENND2B; HeLa tumor suppression 1; HTS1; p126; p70; St5; suppression of tumorigenicity 5; suppression of tumorigenicity 5 protein | |
Rabbit | |
Affinity chromatography | |
RUO | |
308944, 6764, 76954 | |
-20°C | |
Lyophilized |
Western Blot | |
500 μg/mL | |
PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal | |
P78524, Q924W7 | |
DENND2B | |
A synthetic peptide corresponding to a sequence in the middle region of human ST5 (571-586aa KRHSHDDMLLLAQLSL). | |
100 μg | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
Safety and Handling
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