Invitrogen™ ST8SIA1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597234

Catalog No. PIPA597234

Description

Immunogen sequence: YRLPNEKEIV QGVLQQGTAW RRNQTAARAF RKQMEDCCDP AHLFAMTKMN SPMGKSMWYD GEFLYSFTID NSTYSLFPQA TPFQLPLKKC AVVGNGGILK KSGCGRQIDE ANFVMRCNLP PLSSEYTKDV GSKSQLVTAN PSIIRQRFQN LLWSRKTFVD NMKIYNHSYI YMPAFSMKTG TEPSLRVYYT LSDVGANQTV LFANPNFLRS IGKFWKSRGI HA; Positive Samples: A-549, SGC-7901; Cellular Location: Golgi apparatus membrane, Single-pass type II membrane protein.

Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. Alternatively spliced transcript variants have been found for this gene.

Specifications

• Antigen: ST8SIA1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: ST8SIA1
• Gene Alias: 9330109E03Rik; alpha-2, 8-sialyltransferase; alpha-2, 8-sialytransferase; alpha-2,8-sialyltransferase; alpha-2,8-sialyltransferase 1; alpha-2,8-sialyltransferase 8A; alpha-N-acetylneuraminate: alpha-2,8-sialytransferase; alpha-N-acetylneuraminide alpha-2,8-sialyltransferase; disialoganglioside (GD3) synthase; ganglioside GD3 synthase; Ganglioside GT3 synthase; ganglioside-specific alpha-2,8-polysialyltransferase; GD3 synthase; GD3S; sialyltransferase 8; sialyltransferase 8 (alpha-2 8-sialytransferase) A; sialyltransferase 8 (alpha-N-acetylneuraminate: alpha-2,8-sialytransferase, GD3 synthase) A; Sialyltransferase 8 (alpha-N-acetylneuraminate: alpha-28-sialytransferase GD3 synthase); sialyltransferase 8 A; Sialyltransferase 8 A (alpha-N-acetylneuraminate: alpha-28-sialytransferase GD3 synthase) GenBank no: U53883; sialyltransferase 8A; sialyltransferase 8A (alpha-N-acetylneuraminate: alpha-2,8-sialyltransferase, GD3 synthase); sialyltransferase St8Sia I; sialytransferase St8Sia I; Sia-T; Siat8; SIAT8A; SIAT8-A; ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 1; ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1; ST8Sia I; St8sia1; ST8SiaI
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6489
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 8.42 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: Q92185
• Gene Symbols: ST8SIA1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 49-270 of human ST8SIA1 (NP_0030251).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG