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Invitrogen™ Stabilin 2 Polyclonal Antibody
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Catalog No. PIPA587617 Shop All Thermo Scientific Products
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PIPA587617 100 μL
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Catalog No. PIPA587617 Supplier Invitrogen™ Supplier No. PA587617
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GKVCTLINVC LTKNGGCSEF AICNHTGQVE RTCTCKPNYI GDGFTCRGSI YQELPKNPKT SQYFFQLQEH FVKDLVGPGP FTVFAPLSAA FDEEARVKDW DKYGLMPQVL RYHVVACHQL LLENLKLISN ATSLQGEPIV ISVSQSTVYI NNKAKIISSD IISTNGIVHI IDKLLSPKNL LITPKDNSGR ILQNLTTLAT NNGYIKFSNL IQDSGLLSVI TDPIHTPVTL FWPTDQALHA LPAEQQDFLF NQDNKDKLKE YLKFHVIRDA KVLAVDLPTS TAWKTLQGSE LSVKCGAGRD I; Positive Samples: HepG2, BT-474, Mouse liver, Mouse eye, Mouse kidney, Rat liver; Cellular Location: Cell membrane, Cytoplasm, Single-pass type I membrane protein.

This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Stabilin 2
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
Gene STAB2
Gene Accession No. Q8CFM6, Q8R4U0, Q8WWQ8
Gene Alias 190 kDa form stabilin-2; 190 kDa hyaluronan receptor for endocytosis; CD44-like precursor FELL; DKFZP434E0321; FAS1 EGF-like and X-link domain containing adhesion molecule-2; FAS1 EGF-like and X-link domain-containing adhesion molecule 2; fasciclin egf-like, laminin-type egf-like, and link domain-containing scavenger receptor-2; fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2; FEEL2; FEEL-2; FELE-2; FELL; FELL2; FELL-2; FEX2; Hare; HAREFELL2; hepatic hyaluronan clearance receptor; hyaluronan receptor for endocytosis; hyaluronic acid receptor for endocytosis; MFEEL-2; SCARH1; scavenger receptor FEEL-2; Short form stabilin-2; stab2; STAB-2; stab2 {ECO:0000250; stabilin 2; Stabilin2; stabilin-2; UniProtKB:Q8WWQ8}
Gene Symbols STAB2
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 192188, 282580, 55576
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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