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STAM2 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501568763
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50-156-8763 20 μL
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Catalog No. 50-156-8763 Supplier Bethyl Laboratories, Inc Supplier No. A304818AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt.

STAM contains an SH3 (Src homology 3) motif as well as an immunoreceptor tyrosine-based activation (ITAM) motif, both of which appear to be required for c-Myc induction in response to IL-2 and GM-CSF. STAM associates with JAK3 and JAK2 via its ITAM region, and it is tyrosine phosphorylated by JAK3 and JAK2 after stimulation with IL-2 and GM-CSF, respectively. STAM2, also known as Hbp, is a protein that is highly related to STAM. Similar to STAM, STAM2 functions downstream of JAK kinases and can be phosphorylated in response to cytokines. Due to alternative splicing events, two isoforms of STAM2 exist, namely STAM2A and STAM2B.

Specifications

Antigen STAM2
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene STAM2
Gene Accession No. O75886
Gene Alias STAM2; signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 ; HGNC:11358; DKFZp564C047; Hbp; STAM2A; STAM2B ; STAM-like protein containing SH3 and ITAM domains 2; signal transducing adaptor molecule 2
Gene Symbols STAM2
Host Species Rabbit
Immunogen Between 175 and 225
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10254
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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