STAM2 Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Supplier:  Bethyl Laboratories, Inc A304818AT

Catalog No. 50-156-8763

Description

The recommended shelf life for this product is 1 year from date of receipt.

STAM contains an SH3 (Src homology 3) motif as well as an immunoreceptor tyrosine-based activation (ITAM) motif, both of which appear to be required for c-Myc induction in response to IL-2 and GM-CSF. STAM associates with JAK3 and JAK2 via its ITAM region, and it is tyrosine phosphorylated by JAK3 and JAK2 after stimulation with IL-2 and GM-CSF, respectively. STAM2, also known as Hbp, is a protein that is highly related to STAM. Similar to STAM, STAM2 functions downstream of JAK kinases and can be phosphorylated in response to cytokines. Due to alternative splicing events, two isoforms of STAM2 exist, namely STAM2A and STAM2B.

Specifications

• Antigen: STAM2
• Classification: Polyclonal
• Formulation: TBS with 0.1% BSA and 0.09% sodium azide
• Gene Accession No.: O75886
• Gene Symbols: STAM2
• Immunogen: Between 175 and 225
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Conjugate: Unconjugated
• Gene: STAM2
• Gene Alias: STAM2; signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 ; HGNC:11358; DKFZp564C047; Hbp; STAM2A; STAM2B ; STAM-like protein containing SH3 and ITAM domains 2; signal transducing adaptor molecule 2
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10254
• Content And Storage: 4° C
• Form: Liquid