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Invitrogen™ Stargazin Monoclonal Antibody (N245/36)
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Catalog No. PIMA527645
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100 μg
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Catalog No. Quantity
PIMA527645 100 μg
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Catalog No. PIMA527645 Supplier Invitrogen™ Supplier No. MA527645
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Description

Mouse Monoclonal Antibody

1 μg/mL of MA5-27645 was sufficient for detection of TARP Gamma2/4/8 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 35-55kDa. Does not cross-react with TARPGamma3. This antibody was formerly sold as clone S245-36.

Stargazin is a member of the transmembrane AMPAR regulatory proteins (TARP) family and is involved in glutamate receptor trafficking. It has been recently demonstrated that the interaction between stargazin and AMPA receptors is critical for the correct localization of the receptors at the synapse. Phosphorylation of the stargazin protein at Thr 321 by Protein Kinase A regulates its interaction with PSD-95 and synaptic targeting of AMPA receptors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Stargazin
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone N245/36
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Gene Cacng2
Gene Accession No. O88602, Q71RJ2, Q9Y698
Gene Alias AW060990; B230105C07Rik; B930041E13Rik; CACNG2; calcium channel, voltage-dependent, gamma subunit 2; calcium voltage-gated channel auxiliary subunit gamma 2; CaV gamma 2; Ipr328; MGC123981; MGC138502; MGC138504; MRD10; Neuronal voltage-gated calcium channel gamma-2 subunit; stargazer; Stargazin; stg; TARP; TARP gamma 2; TARP gamma-2; Transmembrane AMPAR regulatory protein gamma-2; voltage-dependent calcium channel gamma-2 subunit; voltage-dependent calcium channel subunit gamma; wag; waggler
Gene Symbols Cacng2
Host Species Mouse
Immunogen Fusion protein amino acids 203-323 (Cytoplasmic C-terminus) of rat TARPGamma2.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10369, 12300, 84347
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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