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STAT2 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501735893 Shop All Proteintech Group Inc Products
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50-173-5893 150 μL
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Catalog No. 50-173-5893 Supplier Proteintech Group Inc Supplier No. 510752AP150UL
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Description

Rabbit Polyclonal Antibody

This antibody is a rabbit polyclonal antibody raised against a peptide mapping within human STAT2. The calculated molecular weight of STAT2 is 98 kDa, but phosphorylated STAT2 is about 100-113 kDa.

CD95 (Fas, APO-1), a 46 kDa transmembrane glycoprotein, is a cell death receptor of the TNFR superfamily. Stimulation of CD95 results in aggregation of its intracellular death domains, formation of the death-inducing signaling complex (DISC) and activation of caspases. In type I cells caspase 3 is activated by high amounts of caspase 8 generated at the DISC, in type II cells low concentration of caspase 8 activates pathway leading to the release of cytochrome c from mitochondria and activation of caspase 3 by cytochom c. Besides its roles in induction of apoptosis, Fas also triggers pro-inflammatory cytokine responses.

Specifications

Antigen STAT2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.23 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene STAT2
Gene Accession No. P52630
Gene Alias ISGF 3, P113, STAT113, STAT2
Gene Symbols STAT2
Host Species Rabbit
Immunogen Peptide
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6773
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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